KMID : 1234420100380030278
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Korean Journal of Microbiololgy and Biotechnology 2010 Volume.38 No. 3 p.278 ~ p.282
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Antibacterial Activity and Component Analysis of Persicaria perfoliata Extracts
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Kim Sun-Young
Won Doo-Hyun Park Soo-Nam
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Abstract
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Research Center for Development of Green Cosmetic ? In this study, the antibacterial activity and component analysis of Persicaria perfoliata extracts were investigated. MIC (Minimum Inhibitory Concentration) values of ethyl acetate fraction from P. perfoliata on Escherichia coli, Propionibacterium acnes, and Staphylococcus aureus were 0.25%, equally. The results showed that the antibacterial activity of the ethyl acetate fraction was the highest in the S. aureus and P. acnes. Ethyl acetate fraction from P. perfoliata extracts showed 5 bands in TLC and 8 peaks in HPLC (320nm). In HPLC chromatogram of ethyl acetate fraction, first main peak 2 (24.99%) and peak 3 (22.65%) were identified as quercetin-3-o-glucuronide and isoquercitrin in the order of elution time. Also, in HPLC chromatogram of deglycosylated fraction, main peak 2 (76.93%) was identified as quercetin in the order of elution time. And these components are very effective as antioxidants. Thus, these results indicate that extract/ fractions of P. perfoliata can be applicable to new functional cosmetics for antioxidant, antibacterial activity.
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KEYWORD
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Persicaria perfoliata, antibacterial activity, methyl paraben, quercetin, flavonoid, cosmetics
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